KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
19.39
Human Site:
S175
Identified Species:
35.56
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S175
S
I
P
P
E
E
M
S
P
E
F
T
T
L
P
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S175
S
I
P
P
E
E
M
S
P
E
F
T
T
L
P
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
S175
S
I
P
P
E
E
M
S
P
E
F
T
T
L
P
Dog
Lupus familis
XP_537198
743
82483
S175
S
I
P
P
E
E
M
S
P
E
F
T
T
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
S175
S
I
P
P
E
E
M
S
P
E
F
S
G
L
P
Rat
Rattus norvegicus
Q5M9F8
807
89107
S192
D
P
P
E
L
A
D
S
S
S
R
A
V
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
A794
A
I
P
P
E
E
L
A
A
E
F
E
T
L
P
Chicken
Gallus gallus
NP_001012613
698
77220
H174
S
S
F
Q
Q
T
L
H
C
T
L
L
N
P
D
Frog
Xenopus laevis
Q561M0
827
91284
K190
P
E
K
T
D
R
S
K
T
S
K
E
K
W
S
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
L175
A
I
P
P
E
E
K
L
E
G
F
K
T
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
V161
R
L
A
G
F
E
Y
V
W
R
A
T
D
V
N
Honey Bee
Apis mellifera
XP_001123124
613
70111
T92
G
S
K
F
F
L
A
T
E
Q
V
K
P
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
K181
Q
A
I
P
P
E
E
K
Q
D
G
V
K
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
100
100
100
N.A.
86.6
13.3
N.A.
66.6
6.6
0
60
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
86.6
20
6.6
66.6
N.A.
26.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
0
0
8
8
8
8
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
8
0
0
8
0
0
8
0
8
% D
% Glu:
0
8
0
8
54
70
8
0
16
47
0
16
0
0
8
% E
% Phe:
0
0
8
8
16
0
0
0
0
0
54
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
8
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
54
8
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
16
0
0
0
8
16
0
0
8
16
16
8
0
% K
% Leu:
0
8
0
0
8
8
16
8
0
0
8
8
0
62
0
% L
% Met:
0
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
8
8
62
62
8
0
0
0
39
0
0
0
8
8
54
% P
% Gln:
8
0
0
8
8
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% R
% Ser:
47
16
0
0
0
0
8
47
8
16
0
8
0
0
16
% S
% Thr:
0
0
0
8
0
8
0
8
8
8
0
39
47
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _